CDK1 and infection: After infection with SFTSV, cells stop at the G2/M transition, and the accumulation of cells at the G2/M transition does not affect viral adsorption and entry, but this does promote viral replication The interaction between viral NSs and CDK1 inhibits the formation of the cell cycle protein B1–CDK1 complex and nuclear import, leading to cell cycle arrest, and the expressed CDK1 loss-of-function mutants reverse the inhibitory effect of NSs on the cell cycle, thereby promoting viral replication [49].