In this paper, we describe the laboratory evaluation and field deployment of two novel immunochromatographic rapid diagnostic test prototypes co-developed by Global Access Diagnostics (GADx) and the Institut Pasteur de Dakar: a dual line test for the detection of IgM and IgG antibodies to dengue virus (DENV1-to DENV4), and a single line test for the detection of dengue NS1 for acute cases. This evidence concerns the gene CD40LG and dengue disease.