As expected [56], KAN0441571C induced dephosphorylation of ROR1 in a dose-dependent manner, as well as EGFR, SRC, PI3K110δ/AKT/mTOR (non-canonical Wnt pathway), and CREB in the NCI-H23 lung cancer cell line (Figure S5). This evidence concerns the gene AKT1 and lung carcinoma.