Although these NGF-functionalised magnetic nanoparticles emerged as a promising ocular-tailored therapeutical nanotool, we decided to move towards an organic drug delivery system to overcome some disadvantages associated with the lack of evidence concerning biodegradability, toxicity and clearance mechanisms, which still pose some issues to the use of iron-based nanomaterials for the treatment of retinal disorders/degeneration. Here, NGF is linked to retinal disorder.