IL1B and rheumatoid arthritis: The oral or intravenous administration of ABP-terminated PPH dendrimers in a mouse model of rheumatoid arthritis (IL-1-ra−/− mice) led to a drastic decrease in the serum levels of pro-inflammatory cytokines (IL-1β, IL-6, and IL-17) and metalloproteins (MMP-3 and MMP-9), which translated in the control of the disease progression and clinical symptoms [168,169].