HNSCC patients with higher tumor expression of IL17RB combined with high expression of either the CD4 Tem, memory B cell, or aNK TS had improved prognosis compared to patients with lower expression of IL17RB and high expression of either the CD4 Tem, memory B cell, or aNK TS (Figure 6, top panel). This evidence concerns the gene CD4 and head and neck squamous cell carcinoma.