Haptoglobin (HP) and serum amyloid A (SAA) have been shown to play a role in viral infections such as caprine arthritis encephalitis, border disease, sheep and goat plague, bluetongue, bovine viral diarrhea, foot-and-mouth disease, and bovine respiratory syncytial virus (BRSV) [15,16,17]. The gene discussed is HP; the disease is plague.