KLF9 and in situ carcinoma: In the KLF9-overexpressing condition, RPMI-7951 cells exhibited significantly lower viability than naïve and ctrl-ad cells, where TMZ, CIS, or CARB reduced cell viability to 47.70% (p ≤ 0.001), 48.32% (p ≤ 0.001), or 48.63% (p ≤ 0.001), respectively.