Pretreatment with FLP significantly reduced the heart weight index and left ventricle weight index, indicative of its cardioprotective ability against infiltration and cardiac damage, in addition to blockade of cardiac 5-HT2A receptors, which was shown to play a major role in cardiac hypertrophy through inhibition of the CamKII/HDAC4 pathway [62]. Here, CAMK2G is linked to cardiac hypertrophy.