INS and obesity due to melanocortin 4 receptor deficiency: Additionally, daily protein intakes ≥1.2 g/kg/day were associated with improved TIR and reduced TAR, but not TBR following MVPA bouts, with significant interaction effects observed indicating that female adolescents, those with overweight/obesity, and those on multiple daily insulin injections may experience greater increases in TIR and greater reductions in TAR with daily protein intakes >1.2 g/kg/day.