DNMT1 and neoplasm: Specifically, we tested whether an extract derived from fruit seeds, lyophilized shells, and dried red grapes, blackberries, blackcurrants, redcurrants, and rosehips under the brand name Fruit Café (ProVitamix, Budapest, Hungary), which contains 100–200 mg/portion/day of polyphenols/flavonoids, could prevent the early stages of tumour formation following carcinogenic DMBA exposure by modulating DNMT and HDAC mRNA levels.