Mirza et al. described results, similar to our findings, for the relative gene expression levels of DNMT1, DNMT3A, and DNMT3B measured by RT-PCR in breast cancer cells treated with multiple natural chemopreventive substances, such as EGCG, genistein, withaferin A, curcumin, resveratrol, and guggulsterone. The gene discussed is DNMT3A; the disease is breast carcinoma.