TP53 and neoplasm: Compared with the CDDP group, CDDP combined with A. muciniphila reduced tumor growth and volume;Compared with the CDDP group, CDDP combining with A. muciniphila, downregulated the levels of ki-67, p53, Fas ligand proteins, and upregulated Fas proteins, increased the levels of proinflammatory cytokines, and reduced the number of Treg lymphocytes in mouse peripheral blood and spleen.