Reduction in macrophage and CD8+ cytotoxic T lymphocyte levels in the colon of mice with DSS-induced colitis;Reduction in markers of DNA damage; cell apoptosis; abnormal proliferation of colonic epithelial cells;Expansion of cytotoxic T-lymphocytes in the colon and mesenteric lymph nodes; modulation of macrophage subpopulations in CAC mice. This evidence concerns the gene CD8A and colitis.