Total IgE elevation correlated marginally with a positive family history of IBD (12.5 vs. 3.8%; chi2 = 3.2, p = 0.07; OR = 3.6 [0.82–15.99], p = 0.09; φ = 0.16) and negatively correlated with complicated disease behaviour (22.5 vs. 41.8%; chi2 = 4.3, p = 0.037; OR = 0.4 [0.17–0.96], p = 0.04; φ = −0.19). The gene discussed is IGHE; the disease is inflammatory bowel disease.