Moreover, treated with another covalent inhibitor of KRAS-G12C ARS1620, the KRAS-G12C mutant cell would present ARS1620-modified peptides in MHC-I complexes, which could serve as tumor-specific neoantigens to elicit a cytotoxic T cell response against KRAS-G12C cells [63]. The gene discussed is KRAS; the disease is neoplasm.