FAP and cancer: In this regard, several research groups have explored strategies for treating various tumors by targeting FAP with small molecule inhibitors [12,13,14,15,16], antibodies [17,18], prodrugs based on FAP’s DPP activity [19,20], CAR T-cells [21,22], and FAP vaccines [23], the latter being due to the genetic stability of CAFs over cancer cells, making it a viable cancer therapeutic target.