Three genes (anti-CCR5 microRNA gene; TRIM5a-HRH gene encoding a modified human TRIM5a protein; and V2O gene encoding C-peptide, a fusion inhibitor) that inhibit the virus at the initial stages of its life cycle and prevent insertion of proviral DNA were selected, as such genes can more effectively protect against infection [10,11,12]. This evidence concerns the gene CCR5 and infection.