LAP3 and infection: One of the most researched PGH is lysostaphin, a 25 kDa peptidase produced by Staphylococcus simulans, that disrupts the peptide link between the third and fourth glycine residues of the pentaglycine cross-link in the S. aureus PG, which was demonstrated to be efficient in infections caused by Staphylococcus spp.