PTGER1 and non-small cell lung carcinoma: COX-2 is an important inflammatory cell mediator and Mudit et al. [25] found that GSP inhibited the growth and accelerated the apoptosis of non-small cell lung cancer cells (A549, H1299, H460, H226, and H157) by suppressing the overexpression of COX-2, prostaglandin E2, and prostaglandin E2 receptors (EP1 and EP4).