MMP9 and neoplasm: By inhibiting the expression of MMP-9 metalloproteinase and interleukin-8 (IL-8) [124], the glycosyl dietary flavonoid luteolin (8-C-d-glucopyranoside) inhibits tumor invasion in 12-O-tetradecanoylphorbol-13-acetate (TPA)-treated MCF-7 breast cancer cells.