It has also been shown that cytotoxic T lymphocytes have a higher rate of proliferation and a lower rate of apoptosis in ITP, which leads to higher levels of IL-2 and IFNγ and lower levels of secreted IL10, alterations that are due to reduced levels and efficacy of Treg cells in patients with active ITP [18]. Here, IFNG is linked to autoimmune thrombocytopenic purpura.