Moreover, we discovered that the TMIGD3 was positively correlated with the markers of M2 macrophages (Figure 6D–F, CD163, membrane-spanning 4-domains, subfamily A, member 4A, mannose receptor, C type 1), macrophages (Figure 6G–H, CD68, integrin, alpha M), and cancer-associated macrophages (Figure 6I–L, CD80, CD86, chemokine receptor 5 and chemokine ligand 2). The gene discussed is CD86; the disease is cancer.