These and other inflammatory mediators, such as adipokines (leptin, adiponectin, vaspin, resistin, visfatin, and omentin-1), cyclophilin A, vascular dysfunction mediators (endothelin-1, vascular cell adhesive molecule-1), NF-κB, and epigenetic regulators (microRNAs) are thought to have a role in the pathogenesis of PCOS and have recently been reviewed [105]. Here, LEP is linked to polycystic ovary syndrome.