TNF and polycystic ovary syndrome: Chronic inflammation is a common finding in women with PCOS, as measured by an increase in multiple markers of inflammation, such as C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-17 (IL-17), interleukin-18 (IL-18), and interleukin-23 (IL-23), and a low level of anti-inflammatory interleukin-10 (IL-10) [27,28,29,30,31,32,33,34,35].