Ginger extract was demonstrated to boost brain SOD and CAT expression, decrease NF-ĸB, interleukin-1 beta (IL-1β), and malondialdehyde (MDA) levels and improve behavioural impairment in a rat model of AD caused by oral AlCl3 and injection of intracerebroventricular β-amyloid protein [206]. Here, IL1B is linked to Alzheimer disease.