Promising new biomarkers in DKD are urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, serum cystatin C, uromodulin, urinary N-acetylo-beta-D-glucosaminidase, the liver-type fatty acid binding protein, and serum interleukin 18 [40]. This evidence concerns the gene HAVCR1 and diabetic kidney disease.