CHEK2 and endometrial cancer: According to the TCGA database, the co-mutation of ATM and ARID1A genes remarkably expanded the scale of TILs in an endometrial cancer cohort (n = 242), and analysis results from another endometrial cancer cohort (n = 567) showed that low mRNA levels of ATM and CHK2 in tumors were positively correlated with intensified TILs [161].