Population: patients who underwent whole-body 18F-FDG PET–CT to identify ACTH-dependent CS source Adenoma detection:- MRI: + in 7/11 (64%), specificity: 72%- 18F-FDG PET–CT: + 4/11 (36%, all also  seen on MRI), specificity: 50%To size:- inconclusive: 18F-FDG + in 0/4 - microadenoma: 18F-FDG + in 3/4 - macroadenoma: 18F-FDG + in 1/3Histological confirmation: yesOutcome: unknown. The gene discussed is POMC; the disease is adenoma.