Christopoulos et al. estimated and compared the genetic, clinical, hormonal, and metabolic characteristics of 183 PCOS women and 148 healthy volunteers and observed that the PPARγ gene polymorphisms do not increase the risk for PCOS (apart from the reduced testosterone levels), whereas the +294T/C polymorphism in the exon 4 of the PPARδ gene led to the elevation of fasting glucose levels [57]. This evidence concerns the gene PPARD and polycystic ovary syndrome.