However, Wang et al. described that PPARγ mRNA and protein levels are seemingly low in the adipose tissue of PCOS-induced rats [87], whereas Nada et al. determined changes in the PPARγ mRNA expression in prenatal testosterone-treated sheep (the metabolic characteristics of which resemble the ones of PCOS women) and revealed low PPARγ levels in the liver, but high PPARγ levels in the adipose tissue [88]. This evidence concerns the gene PPARG and polycystic ovary syndrome.