BDKRB1 and cardiac arrhythmia: Notably, we found that R-954 had multiple cardioprotective effects: the daily blockade of B1R (120–160 dpi) attenuated chronic myocarditis, reduced mortality indexes, and ameliorated the conduction abnormalities that are associated with CCC, including QRS (which reflects the duration of the depolarization of both ventricles) and QTc interval (a prolonged QT interval is usually a predictor to increased risk of arrhythmias).