We also evaluated subclinical markers of atherosclerosis (IMT, interventricular septum (IVS), the ankle-brachial index (ABI)), the main cardiovascular risk factors such as C reactive protein (CRP), mineral metabolism (serum calcium and phosphorus, intact parathormone (iPTH), 25-hydroxyvitaminD (25-OH-VitD)) and metabolic indexes (serum uric acid (SUA), total cholesterol, serum triglycerides, serum glucose and insulin) as possible predictive factors of CIAKI. The gene discussed is CRP; the disease is atherosclerosis.