Univariate logistic regression analysis showed nine factors associated with UHR MM: age > 65 years, HGB < 100 g/L, LDH > 250 U/L, SCr > 2 mg/dl, CsCa > 2.75 mmol/L, BNP or NT-proBNP > 2 ULN, Barthel index score, high risk CAs, and ISS stage (Table 3). This evidence concerns the gene NPPB and Miyoshi myopathy.