COL3A1 and Alzheimer disease: We have found that rs1800255 polymorphism in the COL3A1 regarding the AA genotype was statistically associated with the occurrence of mild SCORAD (OR = 0.16; 95% Cl: 0.03–0.78; p = 0.02), while the GG genotype was significantly associated with severe AD measured by SCORAD (OR = 6.6 (95% Cl: 1.23–32.35, p = 0.03) (Figure 1).