The association between mortality risk and elevated inflammatory biomarkers in patients with severe COVID-19 pneumonia was supported by several studies [29,30,31], while elevated serum CRP, PCT, D-dimer, and serum ferritin levels were associated with an increased composite poor outcome that included mortality, ARDS, and the need for ICU admission in patients with COVID-19 [32]. This evidence concerns the gene CRP and acute respiratory distress syndrome.