Disease severity has been shown to depend on numerous risk factors, such as demographic characteristics (age, sex ethnicity), comorbidities, the presence of organ dysfunction, or systemic inflammation, which most times is implicated by the elevation of specific biomarkers, such as plasma creatinine, troponin, C-reactive protein (CRP), ferritin, D-dimers, or hepatic failure indicators (AST/ALT) [9,10], or it could be related to the severity of respiratory failure [11]. The gene discussed is CRP; the disease is respiratory failure.