HDAC6 and HIV-1 infection: HDAC6 is an enzyme that promotes the deacetylation of the α-tubulin subunit in microtubules (MTs), thereby modulating cytoskeleton dynamics [13,14,15,16,17,18] and the first steps of the HIV-1 infection process [15,19,20], as well as the regulation of HIV-1 replication and infectious ability by promoting the autophagy-mediated clearance of several viral factors (e.g., Pr55Gag and Vif) [21,22].