TARDBP and HIV-1 infection: We characterized the effect of two TDP-3 constructs that have previously been assayed on HIV-1 infection studies [12] and well characterized in other biological functions [11,12,26,27,28]: a full-length N-terminal Flag-tagged, wild-type TDP-43 construct (Flag-wt-TDP-43), and an N-terminal Flag-tagged nuclear localization signal (NLS) mutant (Flag-NLS-mut-TDP-43) that lacks the NLS domain of the protein [11,12,26,27,28], as we previously characterized in HIV-1 studies [12].