IL10 and erythema multiforme: Serum IL-6 and TNF-α in the EM group at days 21 and 42 were lower than the NC group (p < 0.05), whereas serum IL-10 in the EM group was higher than the NC group (p < 0.001); however, there were no significant differences in serum IL-1β (Figure 3B,D).