CD274 and neoplasm: In this study, the objective response rate (ORR) was 19% in patients with <1% PD-L1 expression in tumor biopsy samples and 26% in patients with ≥1% PD-L1 expression in tumor biopsy samples using a PD-L1 IHC 28-8 pharmDx assay; however, this difference did not reach statistical significance.