In particular, they found an association between regular use of aspirin and reduced risk of developing CRC in individuals carrying the TT genotype of SNP rs2965667, which is located on chromosome 12p12.3, near the microsomal glutathione S-transferase 1 (MGST1) gene, and in individuals carrying the AA genotype of SNP rs16973225, which is located on chromosome 15q25.2, near the interleukin 16 (IL16) gene (Table 2) [86]. Here, IL16 is linked to colorectal carcinoma.