As the presence of TNFR2 in the blood and TME has been associated with unfavorable prognosis in several types of cancer [52], it is possible that the presence of TNFRSF1B rs2275416 may also affect PCa prognosis, given its association with both GS and PSA levels. The gene discussed is TNFRSF1B; the disease is posterior cortical atrophy.