GSTM1 and malaria: Although no significant differences were found in exosomal miR-451a or let-7i-5p levels between sickle Hb genotypes with (+) and without (-) malaria, HbSS- had higher levels of exosomal let-7i-5p (as shown in Figure 4D) compared to HbSC- or HbAA- (as shown in Figure 3B).