GSTM1 and malaria: Exosomal miR-451a levels were slightly higher in HbSS- compared to other sickle Hb genotypes without malaria (as shown in Figure 4I), but all sickle Hb genotypes showed a similar trend in overall exosomal miR-451a levels when RBCs were infected with malaria, as with let-7i-5p (as shown in Figure 4L).