Correspondingly, the current authors suggest that the activated K2P channel, through the TASK1 channels, could accelerate this neuroimmune-induced sensitization on the spinal level in autoimmune diseases with concomitant exaggerated LC activation that could also lead to a morphological picture of upregulated regeneration activity of Piezo2-containing somatosensory axons in the cornea. Here, KCNK3 is linked to autoimmune disease.