Specifically, we used [18F]-N-(2-(2-fluoroethoxy)benzyl)-N-(4-phenoxypyridin-3-yl)acetamide ([18F]FEPPA), a second-generation TSPO tracer, to simultaneously assess cardiac and neural inflammation in a dystrophin-deficient mdx:utrn(+/−) mouse model with one functional utrophin protein (Figure 1), known to exhibit moderate to severe disease phenotypes that better mimic human cardiomyopathy symptoms [24]. Here, UTRN is linked to cardiomyopathy.