EP300 and posterior cortical atrophy: Bromodomain adjacent to zinc finger domain protein 2A (BAZ2A), a bromodomain (BRD)-containing protein, recognized histone acetyltransferase p300 (EP300)-mediated H3K14ac marks and suppressed the transcription of differentiation-related genes such as aldehyde oxidase 1 (AOX1), DNA damage-binding protein 1 (DDB1), beta-mannosidase (MANB2) and dystrophia myotonica protein kinase (DMPK), maintaining the stemness stage of PCa [163].