Flow cytometry analysis of the composition of T-cells producing IFN-γ (Th1), IL-17A (Th17), IL-4 (Th2), and IL-10 (Treg) revealed no visible changes in the percentage of Th1 and Treg cells in response to various exosomes for both MS patients and control subjects without autoimmune disease. This evidence concerns the gene IL4 and autoimmune disease.