TGFB1 and keratoconus: Differentially expressed genes identified in HKCs (TGFβ1 + CMS) vs. HCFs (TGFβ1 + CMS) were enriched in several pathways such as WNT signaling, regulation of apoptosis process, collagen fibril organization, and degradation of extracellular matrix, all of which have been implicated in KC pathogenesis [70,71,72,73,74].