Interestingly, some of these genes, such as ADAMTS15, HDAC5, COL16A1, COL7A1, COL4A2, WNT2, LAMA3, ITGA10 and AQP1 have been identified as KC-related genes or expressed in the cornea [38,62,63,64,65,66,67,68,69]. The gene discussed is WNT2; the disease is keratoconus.