Likewise, it is possible to detect lncRNAs with the use of other techniques with higher sensitivity, such as ISH-RNA, which has been used for the rapid detection of markers, such as HER2 in breast cancer, [82] with greater sensitivity and specificity (99% and 98%, respectively) when compared to HER2 immunohistochemistry (IHC) assay detection (95% and 98%, respectively) [83]. This evidence concerns the gene ERBB2 and breast cancer.