According to data, NB has a genetic preset; the main genetic changes proved are the chromosome 1p36 deletion (around 70% of cases), chromosome 17q gain (around 80% of cases), 2p24MYCN proto-oncogene (myelocytomatosis viral oncogene neuroblastoma derived homolog) amplification (around 25% of cases), anaplastic lymphoma kinase oncogene (ALK) point mutations, or decreased expression of chromodomain-helicase-DNA-binding protein 5 (CHD5) level [2]. Here, CHD5 is linked to neuroblastoma.