As shown in Table 1, a consistent pattern of decreased TC, HDL-C, and LDL-C levels was identified to be correlated with the following clinical parameters: male sex, Binet stage B/C, high CLL-IPI, low Hb, platelet and albumin levels, and high β2-MG level. This evidence concerns the gene GSTM1 and B-cell chronic lymphocytic leukemia.