CEACAM5 and colorectal carcinoma: There are some less invasive techniques; however, these are non-specific for CRC because of their presence in other pathologies, in addition to their presence in late stages of CRC, such as carcinoembryonic antigen (CEA) detection in plasma, as well as the detection of carbohydrate antigen 19-9 (CA19-9), tumor-associated glycoprotein 72 (TAG-72), and tissue polypeptide-specific antigen (TPS) in serum [4].