PTH and Hypercalcemia: Furthermore, at the onset, a low value of PTH and 1,25-dihydroxy vitamin D (1,25(OH)3D) was noted in the context of significant hypercalcemia secondary to the inadequate secretion of 1,25-dihydroxy vitamin D (1,25(OH)2D) from the macrophages of sarcoidotic granulomas and a lack of hydroxylation in the kidney.