Numerous studies have shown that Tea polyphenols (TPs) can alter a number of signaling pathways in cancer cells, including the mitogen-activated protein kinase pathway, PI3K/Akt pathway, Wnt/β-catenin pathway, and 67 kDa laminin receptor pathway, to inhibit proliferation and promote cell apoptosis [48]. The gene discussed is AKT1; the disease is cancer.